Author Archives: Mustafa Abdoh

Cover Letter (Mustafa Abdoh)

18 March 2016

Dear Dr. Maha:

Shadowing a medical professional would prove to be an invaluable and enriching experience from which I may commence delving into the medical field. As an undergraduate at UNC Chapel Hill enrolled as a biomedical engineer major and chemistry minor on the pre-med track, I am fully prepared to handle the responsibility and deliver with the upmost sincerity and efficacy in my work in your clinic. I am eager to learn from and contribute to the working environment of the clinic and observe the professional in practice.

I believe that my qualifications, especially in communication make me a prime candidate for this position. Understanding that this experience takes place in Amman Jordan, it is essential to have a shadow who is fluent in Arabic and English. I meet and excel in this regard as I am fluent in both these languages and have advanced proficiency in French and moderate proficiency in Russian. Along with the language qualification is the ability to interact sociably and professionally with patients. Having worked at Subway, I am adept in interacting and servicing customers in an amicable fashion. Making clients feel comfortable when receiving services is essential in maintaining satisfaction in a restaurant setting. Such skill translates fluidly to medicine. Communication with incoming patients in a professional and sociable manner promotes and maintains a positive, productive working environment.

There is also the matter of taking orders and following directives. I have volunteered under several organizations, where communication between project managers and volunteers was necessary for successful service work. When working on a project for Habitat for Humanity, strict adherence to the task which the group leader assigned proved commitment for the task at hand. I also did not shy away from asking for assistance when something was unclear in order to put the task and safety of others before my pride. Such initiative brought me to excel in following orders and efficiently executing tasks in a timely manner.
Even in the absence of explicit directive, such as when tutoring school children in math, I have exercised improvisation and problem solving skills. Self-direction prevails in tutoring. While the ultimate goal is clear, the path by which to properly teach someone is not universal. I had to shape unique techniques to tackle the problems of each individual tutee. Tutoring demonstrates an understanding for the situation at hand and an ability to respond resourcefully.

Combining the aptitude to apply myself and the willingness and experience to deal with people yields an ideal skill set for this position. Shadowing at your clinic is a window from which I may gain an understanding of the medical world in which I aspire to excel. I have an intense passion for helping and serving others, and this marvelous experience is an outlet for which this passion can be expressed.

Sincerely,

Mustafa Abdoh

Internship Profile

I plan to be a shadow in my aunt’s Private Dentistry Clinic in Amman Jordan over the summer. The shadowing term will last in the period of June 15-July 30. I will accompany my aunt to the clinic whenever she goes during this time. It will be up to her discretion the amount of hours I spend shadowing each day. Daily tasks include the shadowing, involving observation of the dentist in practice, working at the desk to manage scheduling and minor errands upon instruction of the dentist, and interacting and communicating with patients as to satisfy their needs.

There are no academic requirements for this specific trip as it is an informal opportunity; however, a resume and CV, as well as a cover letter will be provided. I will also translate these documents into Arabic so there will exist both English and Arabic forms. The only requirement other requirement is that I be at least proficient in Arabic.

There exists no post-internship presentation or product which I must produce due to the informality of the opportunity.

The main advantage of this opportunity is that it is a private practice located in a foreign country. The fact that it is a private practice allows for an informal atmosphere in which greater interpersonal interactions can take place with the professional and patients. I would not be limited to mere office work, instead actively experiencing the operations taking place. The opportunity also allows for practice of foreign language and cross cultural communication.

This opportunity is not structured through any organization. As such, I will not be able to apply for experiential education credit nor gain any certifications. I will gain experience and exposure to medical practice. The variability in hours is typical of informal shadowing and does not guarantee a set number of hours, necessitating flexibility in my personal scheduling to meet the needs of the dentist.

In terms of lodging, I will be staying at my grandmother’s house in Amman for the whole stay. I will receive transportation two alternate ways. When my aunt is able, she will accommodate me with rides to the clinic. If she requests that I arrive while she is already at the clinic, I will take a taxi. If I am dismissed for the day from my work before my aunt leaves, I will also take a taxi on return. This work is strictly unpaid volunteering, where exposure is the primary gain. As I will be lodging with my grandmother, food is provided. The cost of one round trip plane ticket is $1800. Aside from this, I will need taxi fare, which should not exceed $30 over the course of the shadowing. There are no other costs directly associated with this opportunity.

Fear, Flee, Fluoride

ShinyTeeth-462by Mustafa Abdoh

    Mass hysteria floods the public psyche, panic in the media, incessant buzzing of rumor emanating from the lips of those around you. You lack the comfort you once knew from the moment you were first vicariously touched by the monster’s invisible hand. No longer can you rest at ease in the once-gratifying presence of a crystalline glass of water now that your eyes are opened to the heinous and insatiable appetite of this venomous fiend.

   There is no place on this earth in which this villain, Fluoride, could possibly reside and simultaneously hold up a respectable reputation as an upstanding compound. Hence forth and forevermore we should ban him from our pipelines and dental products and return to a time before the introduction of “big government’s” proxy in human extermination (for the obvious reason that governments are just too lazy to do the killing themselves!) By and by, if we’re going to die, why not get to know the reaper before he reaps?

fluoride

Propaganda and lies!!!

     Fluoride, as it likes to be called, can really be thought of as a coalition group of chemical compounds containing the element fluorine (chemical symbol F). Fluorine can be considered the biological parent of all fluoride compounds, but interestingly enough you can’t find it isolated in nature because it is so electronegative. This property of fluorine means that if it is alone in the wild, it’ll ravenously grab the nearest element’s electrons and never give them back, much like a spoiled toddler.

    Unlike fluorine, which as we’ve said you’ll never find unless you are at the scene of a sun gone supernova, fluorides are literally everywhere, in small doses that is. Fluorides occur naturally in water and soil, as well as trace quantities in the air from various pollutants.

   I am confident you can grapple with the idea that fluorides are everywhere, but surely you are content knowing that the chemical is far from entering your loved ones’ bodies (and yourself, because you love yourself no?) Of course you are! And I proceed with even greater certainty that the structural integrity of your very being would be better off if it never even heard the name fluoride again. Yes indeed, pay no mind to the fact that fluorides are essential to the fortification of bone and teeth, and that your body contains the appropriate mechanisms for responding to excesses of the compound.

     Actually, maybe you should pay mind to that, literally devote all your attention to this last sentence. That image of a scythe-wielding fluoride molecule floating around and tearing up your innards might not hold up to all the hype. Perhaps those sweaty palms and shaky knees, which arise from the compounds mentioned, might not be due to its ill effects but rather due to a mild case of xenophobia (what is fluoride, Latin? That’s so foreign).

    To find a cure, let’s start close to home – with bones. Bones are structured in a lattice network, an ordered and repetitive organization of molecules, comprised of a compound called carbonated hydroxyl apatite. This compound is responsible for maintaining bone strength. When fluoride is absorbed from the bloodstream into the bone, it is dispersed throughout the bone lattice and randomly replaces the hydroxyl groups from some of the apatite molecules, creating carbonated fluoroapatite.

fluoroapatite

This is in your bones, pretty isn’t it, it has phosphate, calcium…… and fluoride

     Despite being a tantalizing name for a fizzy mouthwash, this compound, which your bones have synthesized, alters bone density and structure as well as increases resistance to acid corrosion, as fluoroapatite is more stable than hydroxyl apatite. Therefore fluoride acts as a preventative agent against osteoporosis at natural levels.

   Now you see that fluoride knows its way around your bones. But from my personal experience, I have never excised a femur to lather it in toothpaste so that I may strengthen some skeleton. Last I checked, toothpaste, a prime source of fluoride, is traditionally meant for teeth. Teeth, while they themselves are not bone, similarly contain hydroxyapatite. The substitution with fluoroapatite in the enamel therefore acts in exactly the same manner and with the same benefits.

    Now imagine a steaming, rich chocolate cake filled with layers of soft lustrous cream and topped with the ripest assortment of your favorite fruit. Excellent work! You employed the expert reinforcement of fluoride to coat your enamel! This is true because fluoride reaches your teeth not by blood but by saliva. Every time you salivate (drool) at the thought or sight of decadent nourishment, fluoride reacts with the dental surface and prevents acid corrosion caused by carbohydrates, like those found in cake.

    Fluoride is also a serial killer, to put it bluntly. You are in an eternal struggle with it in every waking moment. You battle the fiend as he eradicates enumerable masses. He takes life without regard. Bacteria never stood a chance. As much as you fed them and nurtured each single celled angel, the heartless beast sought them out and took them from you with frigid efficacy.

    The war effort was launched by our ancestors after the industrial revolution. A dramatic increase in grain and sugars boosted life expectancy and allowed the peoples to follow god’s promise and multiply fruitfully. But the increase in fruit and other delicacies in the human diet have allowed the colonies of naturally occurring bacteria in our mouths to multiply to absurd levels, giving rise to dental caries, or in mundane speech, cavities.

    The primary culprit in the causation of corrosive caries is none other than streptococcus mutans. Researchers conducted a comparative study to discern the efficacy of fluoride toothpastes in contrast to their natural counterparts. The results revealed that the “zone of inhibition” where the bacteria could not cross was largest in the fluoride group. The natural toothpastes also had zones of inhibition, yet the fluoride content contributed significantly to the repulsion of the bacterial horde.

index

The face that launched 1000 brushes

    To be frank, the visage of fluoride, like many other topics strewn into the media limelight, has been distorted beyond reason; however, such phenomenon is not without cause. Like every stereotype, there is truth in the sea of illusion engulfing fluoride.

   You remember fluorine right? Fluorine is designated as a trace element required for our continued existence, like selenium or iodine. It is called “trace” due to the miniscule concentrations in which it is present, leaving only traces of it for us to observe. The issue arises when fluoride concentrations exceed appropriate levels, where the once benevolent champion of pearly white goes from Dr. Jekyll to Mr. Hyde.

   The ultimate irony in fluoride poisoning is that all of the positive effects fluoride strives to uphold are actually reversed. Basically, this amounts to your teeth and bones corroding due to skeletal and dental fluorosis.

   Fluorosis (both of the dental and skeletal variety) occurs when the fluoride molecule competes with the other molecules for the calcium in the body, destroying the crystal lattice of bone and enamel; it renders them porous and unstable like brittle sponges.

   However that’s only the irony. The real problem is not that you will be a spineless gum-toothed jellyfish, but that fluoride will also attack your DNA.

      Fluoride is processed rather well by the liver; elevated blood concentrations of fluoride last no more than an hour, after which excess awaits you to visit the porcelain palace to empty your bladder. When an overdose occurs, however, the liver cells will take in fluoride. This process was observed in a study on rats.

     Several groups of rats were given increasing levels of up to 200ppm (parts per million) of sodium fluoride in their drinking water with the control group receiving no added sodium fluoride. Unbeknownst to the rodents, the extra fluoride-salty water they were consuming encouraged apoptosis, or cell death, in the liver.

     The fluoride activates this gene expression for p53 and caspase-3 proteins, encouraging the self-destruction of the cells. The fluoride actively alters the DNA to further encourage the transcription and production of these proteins. As more cells burst, the livers swell and the rat is slowly stripped of its bio toxin filter.

   Despite the fact that these rats were given 12-50 times the appropriate levels of fluoride, people fear fluoride. In Australia, groups and individuals have levied all of the arguments as to why water fluoridation is a bad idea, going as far as linking water fluoridation to the Nazis and lowered child IQ.

nazi-fluoride-myth

It has fluoride in bold and black and white, it has to be true!!!

      In this particular Australian case, the public health care costs due to dental caries outweighs the costs of water fluoridation seven-fold. While fluoridated water is already available to 85% of the population as of 2009, the debate continues, with both sides shouting science and hysteria on the matter of fluoride. Yet the question remains, how much is safe?

       If we leave the land down under and return to the land from sea to shining sea, we find that in 2011, the shimmering pools of fluoridated water were found to contain concentrations of fluoride that, while previously deemed safe, are now considered too high. The U.S Department of Health and Human Services lowered the previous fluoride level from 4ppm to a mere range of 0.7-1.2ppm. Changes like these, and the expanding body of research on the subjects of water fluoridation, are what fuels the fiery debate like that in Australia. But at the end of the day, we can always blame the Nazis and fluoride for why we failed that 9th grade geometry test.

       So, fluoride can literally change who you are on the inside, for better or for worse, kind of like a best friend. Too much of a best friend can tear you apart, but just enough will give you the support you need to live a prosperous and joyous life.

Fear Flee Fluoride – Query Letter

Mustafa Abdoh
515 Paul Hardin Drive
Chapel Hill, NC 27415
mabdoh@live.unc.edu
February 4, 2016

Dear Ms.Boyd

I Mustafa Abdoh, an aspiring blog-post writer for health topics, implore you to graciously honor me in this letter by gracing these humble lines of text with your knowing and learned eyes. I pray that in this query, your visage not reflect the jaded expression brought about by the skimming of a mundane proposal, but rather your face illuminates in recognizing the contested topic of the effects of fluoride on human health as an invaluable addition to your journal Science. I invite you to enter the murky realm of fluoride, so that you may yourself, gain clarity on such a vital topic.
               Fear Flee Fluoride
Mass hysteria floods the public psyche, panic in the media, incessant buzzing of rumor emanating from the lips of those around you. You lack the comfort you once knew from the moment you were first vicariously touched by the monster’s invisible hand. No longer can you rest at ease in the once gratifying presence of a crystalline glass of water now that your eyes are opened to the heinous and insatiable appetite of this venomous fiend. There is no place on this earth in which this villain, Fluoride, could possibly reside and simultaneously hold up a respectable reputation as an upstanding compound. Hence forth and forevermore we should ban him from our pipelines and dental products and return to a time before the introduction of “big government’s” proxy in human extermination (for the obvious reason that governments are just too lazy to do the killing themselves!). By and by if we’re going to die, why not get to know the reaper before he reaps?

Fluoride, as it likes to be called, can really be thought of as a coalition group of chemical compounds containing the element fluorine (chemical symbol F). Fluorine can be considered the biological parent of all fluoride compounds, but interestingly enough you can’t find it isolated in nature because it is so electronegative. This property of fluorine means that if it is alone in the wild, it’ll ravenously grab the nearest element’s electrons and never give them back, much like a spoiled toddler. Unlike fluorine, which as we’ve said you’ll never find unless you are at the scene of a sun gone supernova, fluorides are literally everywhere, in small doses that is. Fluorides occur naturally in water and soil, as well as trace quantities in the air from various pollutants. I am confident you can grapple with the idea that fluorides are everywhere, but surely you are content knowing that the chemical is far from entering your loved ones’ bodies (and yourself, because you love yourself no?). Of course you are! And I proceed with even greater certainty that the structural integrity of your very being would be better off if it never heard the name fluoride again. Yes indeed, fluorides are in no way essential to the fortification of bone and teeth, nor does your body contain any mechanism built for responding to excess of the compound.

In the full version “Fear Flee Fluoride”, we will be exploring the nature of fluoride and both the pros and cons of its existence in our waters and in our toothpastes. Fluorides will be touted as the defenders against dental caries and bastions from osteoporosis. The means by which fluoride is attained each day will certainly be examined, and as alluded to previously, it is largely from water. Information from a case study in India will be explored as we venture into the various circumstances surrounding fluoride deficient and excessive areas and the health effects on resident populations. The article will then take a riveting turn to explore more negative effects of fluorides on the body. How did excess of fluoride effect lab rats’ DNA for example, and what happens if you brush your teeth too much? Once more the blog will shift to explore the attitudes of the Australian public in the fluoride debate and common concerns will be falsified and verified. This will include statistics on the health care costs concerning water fluoridation and its absence. For those who still fear and wish to escape by way of alternate toothpastes, we will find that according to a simple study, fluoride is in fact a killer… of bacteria. Finally, tips will be provided on how to spot the harmful effects of fluoride overdose and how to stay an informed consumer of fluoridated products like water.

I hope that this article intrigues as well as entertains, and look forward to your response.
Thank you,
Mustafa Abdoh

Fluoride annotated bibliography

Dhar, Vineet, and Maheep Bhatnagar. “Physiology and Toxicity of Fluoride.” Indian Journal of Dental Research 20.3 (2009): 350-5. ProQuest. Web. 25 Jan. 2016.

  • This scholarly journal from the Indian Journal of Dental health delineates to various aspects of the element fluorine and how it exists in relation with the environment and its direct effect on the human population. The article opens with a brief discussion on the nature of the fluoride compounds and their various states in nature. Such is followed by a transition to a specific case for the availability of fluoride, India. Variation in fluoride levels are compared as well as the measures taken to ensure that the proper intake is met for a healthy populous. The article continues to outline the various positive and ill effects that fluoride has on humans of varying age demographics; for the ill effects, the article proposes various diagnoses and treatments for dental and skeletal fluorosis. The topic of genetic mutations due to excess fluoride exposure is briefly discussed.

Gutierrez-Salinas, Jose, et al. “Exposure to Sodium Fluoride Produces Signs of Apoptosis in Rat Leukocytes.” International Journal of Molecular Sciences 11.9 (2010): 3610-22. ProQuest. Web. 25 Jan. 2016.

  • This is a research study on the effects of excess fluoride on the liver of rats and the genetic structure in liver cells. It was found that high doses of sodium fluoride (NaF) caused an overall decrease in the rats’ body weights and increase in liver weights. The findings asserted that because the liver is most subject to toxic substances due to its detoxification role as an organ, it most heavily manifests the effects of fluoride excess. The liver was found to be swollen and ultimately possessed a scrambled cellular structure. It was also found that fluoride ions alter the gene expression of certain liver cells in charge of killing bacteria and cell homeostasis. Fluoride ions, in conclusion, encourage apoptosis of the liver cells, alluding to a similar reaction in human cells.

Schultz, Dodi. “Flouride: Cavity-Fighter on Tap.” FDA consumer 01 1992: 34. ProQuest. Web. 25 Jan. 2016 .

  • The article from FDA Consumer employs reference to the historical success of fluoridation as a means of curbing dental carries. It further continues by explaining how fluoride helps protect teeth through molecular interactions. The article then shifts to discuss the ill effects of fluoride excess on teeth and addresses arguments against fluoridation by a case study with rats in which the research mislead the public by suggestion of a weak (in fact nonexistent) link between fluoride and cancer in rats. The article concludes with a guide and tips informing the reader on the situations in which fluoride supplements should be administered and how certain sources of fluoride in water and other common various sources compare.

 

 

 

 

Lo Giudice, John-Paul. “The Water Fluoridation Debate.” Journal of the Australian – Traditional Medicine Society 20.4 (2014): 274-7. ProQuest. Web. 28 Jan. 2016.

  • This article addresses the various arguments of the debate over the fluoridation of water. The article employs an Australian perspective to the debate. The opening of the analysis compares the cost effectiveness of fluoridating the water to the healthcare costs as a result of dental caries (cavities). The statistic presents the efficacy ratio to be 7:1. The article transitions to various extreme counter arguments and discredits them by alluding to a lack of research in support of and mounted evidence to the contrary of these claims. The article then addresses more valid concerns in the debate against fluoride, finally concluding on a note of indecision, emphasizing the complexity of the issue.

 

Kurian, Maria, and R. V. Geetha. “Effect of Herbal and Fluoride Toothpaste on Streptococcus Mutans – A Comparative Study.” Journal of Pharmaceutical Sciences and Research 7.10 (2015): 864-5. ProQuest. Web. 28 Jan. 2016.

This is a research study comparing the efficacy of fluoride toothpaste versus herbal toothpaste against Streptococcus Mutans, a common bacteria that causes dental caries (cavities). The study was conducted by observing the inhibitory effect of each toothpaste as applied over a set surface area. It was found that the fluoride toothpaste was more effective at preventing the spread of the bacterial population. The study gives proof for an added benefit of fluoride as an antibacterial agent when administered appropriately.

Autism Article Summary

This article opened up with Billy, a man from a New England town in the late 1800’s, undergoing a check up from a doctor recording his characteristics and idiosyncrasies with relation to his “idiocy”. The fact that Billy, and many others before the 1920’s exhibited remarkable mental abilities despite their awkward mannerisms with social interactions and comprehension of certain elements in their environments serves as a basis for the article to argue that autism rates might not necessarily be on the rise, rather, its recognition and scope by which it is diagnosed has merely increased.